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1. Spinal stimulation can be extremely helpful for patients with neuropathic pain, including CRPS. The biggest advantage of this intervention is that it is reversible--if a trial of stimulation is not helpful, no permanent damage is likely to have been experienced. Even if the pain relief is not as robust after several years as recently reported * ; , for this patient, who is refractory to other less invasive treatments, spinal stimulation may provide sufficient pain relief to be beneficial from a functional recovery viewpoint. Regrettably, long-term benefit has not been established for many of the pain interventions commonly used. However, there is a 25% chance of increasing the pain when a sympathectomy is performed, and whether this increase is permanent or not cannot be predicted. While no study has shown. If by a miracle, an inhabitant of ancient Palestine say a subject of Hezekiah, King of Judah, a contemporary of the Prophet Isaiah were to pay us a visit, many things would amaze him: the cars, the airplanes, etc., etc. Joining us at the dinner table, he would no doubt be surprised to find out that the average yearly wine consumption per capita in modern Israel is as little as 4.2 liters and cetirizine. Since fiscal 2005, and the resulting distribution services agreement "DSA" ; fees, totalled $2.7 million for the year ended September 30, 2006, are deducted from revenues. In the fourth quarter ended September 30, 2006 the Company chose to adopt the classification of these fees as a deduction from sales. Previously, these fees were included in selling and administrative expenses. As a result, sales were reduced by $2.7 million in the fourth quarter of fiscal 2006. Fees associated with these agreements incurred in 2005 were not material. It is possible that changes in wholesaler buying patterns may occur in the future, and these changes could result in a reduction in our revenues and could have detrimental effect on our overall financial condition or trends in results of operations. Axcan must be able to continue to manage rapid growth. Largely as a result of past acquisitions of products and companies, Axcan has experienced a substantial increase in sales and in the number of its employees. Since September 30, 1998, the number of employees increased from 79 to 425. In addition, as a result of acquisitions, the Company has expanded into Western Europe. Axcan's employees in Europe now represent 31% of the workforce. Axcan's failure to manage such growth effectively and to continue to improve and consolidate its management controls, reporting systems and procedures would reduce profitability. Axcan relies on third parties for the supply and manufacture of certain products and loss of access to such third parties would impair its ability to carry on business. Axcan depends on third parties for the supply of active ingredients and for the manufacture of most of its products. The Company may not be able to obtain the active ingredients or products from such third parties; the third-party suppliers and manufacturers may not be qualified by regulatory authorities to act as its suppliers and manufacturers; the active ingredients or products may not comply with specifications; the prices at which Axcan purchases active ingredients and products may increase significantly; the Company's suppliers and manufacturers may experience shutdowns or contaminations of their facilities; and, in any such event, Axcan may not be able to locate alternative sources of supply in a reasonable time period, if at all. If any of these events occur, the Company may not be able to continue to market certain of its products and its sales and profitability would be adversely affected. Axcan may not be able to acquire new products or businesses. Axcan's products are maturing and therefore a significant component of its strategy is growth through acquisitions. However, the Company cannot be certain that it will be able to identify appropriate acquisition candidates. If an acquisition candidate is identified, there can be no assurance that Axcan will be able to successfully negotiate the terms of any such acquisition, finance such acquisition or integrate such acquired product or business into its existing business. Axcan faces significant competition from other pharmaceutical companies, which makes it more difficult to find attractive transaction opportunities for products or companies on acceptable terms. Furthermore, the negotiation of potential acquisitions could divert management's time and resources and require significant financial resources to consummate. Failure to acquire new products may diminish the Company's rate of growth and adversely affect its competitive position. Acquisitions that Axcan may undertake will involve a number of inherent risks, any of which could cause the Company not to realize the anticipated benefits. Acquisition transactions involve various inherent risks, such as assessing the value, strengths, weaknesses, contingent and other liabilities and potential profitability of the acquisition; the potential loss of key personnel of an acquired business; the ability to achieve identified operating and financial synergies anticipated to result from an acquisition and unanticipated changes in business, industry or general economic conditions that affect the assumptions underlying the acquisition. Any one or more of these factors could cause Axcan not to realize the anticipated benefits from the acquisition of businesses or products. Axcan's failure to obtain FDA approval for ULTRASE, one of its key products, will impair its ability to generate sales and profits. In April 2004, the FDA formally notified manufacturers of pancreatic insufficiency products that these drugs had to get approval by the FDA before May 2008 in order to remain on the market. The FDA decided to require approval of NDAs for all pancreatic extract drug products after reviewing data that showed substantial variation among currently marketed products. Axcan's enterically coated pancreatic enzyme minitablet formulation marketed under the trademark ULTRASE accounted for 13.2%, or $38.7 million, of sales for fiscal 2006. If Axcan were unable to obtain FDA approval to market ULTRASE, it would no longer be able to sell ULTRASE in the United States, which would impair its results of operations and liquidity.
Table 5 shows the results of applying the discriminant analysis between pathologies 1 and 2. The number of episodes for pathology 3 was too low for it to be considered for this type of study. Patient classification into clinical groups was performed using the database information. The analysis was carried out with all variables VLF, LF and HF ; and for all four regions. The result of the classification was 89.5% of cases being correctly classified with a Wilks lambda of 0.432 p50.05 ; . The Wilks lambda is a multivariate measure of group differences over several variables. As lambda is a type of inverse measure, values of lambda that are near zero denote high discrimination between groups and cinnarizine, for example, azithromycin.
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Tots els apartats que hi ha en aquest pster, s'han publicat posteriorment i molt ms ampliats en l'article correponent a Medicina Clnica, de l'any 2001. Per aquesta ra i per no duplicar la informaci, s'ha pensat adient no exposar mpliament aquest pster. The Dalhousie Medical Research Foundation stepped up to the plate with generous funding for the Kathryn Allen Weldon Chair in Alzheimer Research. This Chair guarantees stable funding for local Alzheimer research in perpetuity, allowing us to build a world-class Alzheimer research program." -- Dr. Kenneth Rockwood Kathryn Allen Weldon Chair in Alzheimer Research Dalhousie University Faculty of Medicine and cisapride. Form of insurance shall be by a Comprehensive General liability and comprehensive Automobile Liability Bodily Injury Each Occurrence $500, 000.00 Aggregate $500, 000.00 Property Damage Each Occurrence $500, 000.00 Aggregate $500, 000.00 Personal Injury Each Person Aggregate $500, 000.00 General Aggregate $500, 000.00 Automobile Liability Owned, Non-owned and Hired Bodily Injury Each Person $100, 000.00 Bodily Injury Each Occurrence $500, 000.00 7. INDEMNIFICATION The successful firm shall hold Sedgwick County harmless from and indemnify it against all liability, including attorneys fees, which may arise from and accure directly from the performance of the work or any obligation of the successful firm or failure of the successful firm to perform any work or obligation provided for in the agreement. 8. CONTRACT PERIOD AND PAYMENT TERMS The contract period with the successful firm will be one 1 ; year, to begin following Board of County Commission approval of the recommended proposal, as finalized, and receipt by the County of any and all required paperwork. The County will have an option to renew the contract for three 3 ; additional one 1 ; year terms, if agreeable between all parties. The County reserves the right to cancel the contract and discontinue services with a fifteen 15 ; day written notice as a result of the failure of the contracted proposer to provide acceptable reports and services as delineated in the response to this document or if determined that services can be better provided by in-house or other sources. Payments for all specified service s ; and or product s ; to the successful proposer can be made with the following criteria taken into consideration: Delivery of the proposed service s ; or product s If required, successful set-up, implementation and or completion of the service s ; and or product s ; delivered; If required, completion of any necessary training to ensure that the personnel will be able to successfully make use of the services and or products; Receipt of a detailed invoice; Final payment won't be made until above conditions are met. 9. TENATIVE TIME LINE The following dates are provided for information purposes and are subject to change without notice. Contact James McComas, Purchasing Department at 316 ; 660-7255 to confirm any and all dates. Distribution of Request for Proposal to interested parties April 21, 2006 Clarification, Information and Questions submitted in writing by 5: 00 p.m. CDT April 27, 2006 Addendum Issued April 28, 2006 Sealed proposals due before 1: 45 p.m. CDT May 09, 2006 Evaluation Period May 10, 2006 May 17, 2006 Board of Bids and Contracts Recommendation May 18, 2006 May 24, 2006 Board of County Commission Award. 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Clinical Audit 8: Audit of Uncomplicated Partner Notification at Sandyford Community Clinics Reason For Audit The Sandyford Initiative protocol for the management of Chlamydia trachomatis infection states that: All patients diagnosed with either chlamydia infection or NGU should see a sexual health adviser. All recent partners should be screened and treated epidemiologically irrespective of findings. In the Sandyford Community Clinics it is not always possible for clients to access the services of a sexual health adviser, but it is important that those clients have access to the same level of care as clients attending Sandyford Central. In the case of Chlamydia trachomatis infection this includes partner notification discussion to be consistent across all Sandyford sites. Partner notification is the process where the health care professional works with the individual diagnosed with an STI to identify, and seek to trace past and present sexual partners. The aim of this process is to allow those sexual contacts identified to be informed of their exposure to an infection and to seek testing and treatment, for example, chlamydia. Arava vaniqa alphagan zyprexa meridia accupril keftab estradiol adalat atarax lopressor nexium nasacort phentblog and clopidogrel.

GOAL To discuss topical and systemic medications used for palliation of recurrent aphthous stomatitis RAS ; . OBJECTIVES Upon completion of this activity, dermatologists and general practitioners should be able to: 1. Contrast the characteristics of recurrent aphthous stomatitis and intraoral herpes simplex virus infection. 2. Discuss topical treatments and their efficacy for RAS. 3. Summarize systemic treatments for RAS. CME Test on page 214.
A number of studies collected in a critical review leads to the conclusion that in healthy individuals the dorsalis pedis, posterior tibial and femoral pulses are not palpable 8.1%, 2.9%, and 0% of the time, respectively7. However pedal and posterior tibial arteries are both absent at the same time in only 0.7% of normal feet since anatomical dissection reveals that hypoplasia of one of these vessels is usually compensated by prominence of the other8. Moreover, the absence of apparent palpable pulses may be often contradicted by the presence of audible arterial flow on further Doppler examination, such that true congenital absence of the dorsalis pedis and posterior tibial artery is seen in only 2% and 0.1% of cases respectively9, 10. The presence of a femoral bruit is an easy and interesting sign to look for since its specificity for PAD defined as defined by an ABI 0.9 is 95% in a large recent study11: indeed, even if the sensitivity of this physical sign in PAD appeared low at 29%, finding its presence confers a likelihood ratio of 5.7 for the diagnosis of PAD Other physical signs of PAD require more experience to interpret correctly and are less reliable than palpating pedal pulses and looking for femoral bruits. The relative diagnostic value of abnormal physical findings is reported in table 7BVII. The performance of the different tests have been selected in accordance with the requisite that PAD is defined as an ABI 0.9 disease present ; or 0.5 severe disease ; viii and cloxacillin.

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Synopsis GW Pharmaceuticals, which has a government license to grow cannabis, said UK patients suffering from terminal cancer will have the opportunity to test cannabis, as it is expanding its clinical trials program. The company said that trials involving patients with MS and spinal cord injury have already produced positive data. More than 100 patients with terminal cancer suffering from pain not unresponsive to current therapy will take part in trials of an under-the-tongue spray of cannabis, at more than 20 centers throughout the country. GW's Executive Chairman has said that around 40% of cancer patients could benefit if the trials are successful and GW was on course to become the first company in the world to win regulatory approval for prescription cannabis-based medicines. They hope to present data to the UK regulatory authorities in 2003, and subject to approval, bring the first cannabis-based prescription medicine to market in early 2004. These authors report injections of this drug through the ear drum once daily for 3 days and danocrine. Title XIX Medical Care Advisory Committees Micheal Bierman, DMD Bruce Bliatout Rita Catapano Donna Crawford Maryann Curry James Davis Rosemari Fitts Michael Garland John Hogan David Strough Rick Wopat, MD Consultants to Health and Social Services Section Thomas Turek, M.D. Medical Director Office of Medical Assistance Programs Department of Human Resources 500 Summer Street, NE Salem, OR 97301 Pharmacy Advisory Task Force Tom Holt, Chairman Mike Dardis, R.Ph. Jim Waletich, R.Ph. Ed Hughes, R.Ph. Ron Dulwick, R.Ph. Jenny Kudna, R.Ph. Dennis Perry, R.Ph. Larry Cartier, R.Ph. Richard Hartmann, R.Ph. Chris Vorrath, R.Ph. Susie Morris, R.Ph. Tom Hornsby, R.Ph. Kathy Ketchum, R.Ph. John Mansfield, R.Ph. Dave Lewis, R.Ph. Dave Walden, R.Ph. Cynthia Wong, R.Ph. Executive Officers of State Medical and Pharmaceutical Associations Oregon Medical Association Robert L. Dernedde, CAE Executive Director 5210 SW Corbett Street Portland, OR 97201 503 226-1555 Oregon State Pharmaceutical Association Tom Holt Executive Director 1460 State Street Salem, OR 97301-4296 503 585-4887.
What is a curious about the Big Spender trials is that Deputy Daniel Garner from the Majors sought to get Ronald Lister to testify. Garner had secretly copied 10 pages from the documents that the Majors had seized then they raided Lister's house in 1986. Garner hoped that the pages would get him off the hook, as the documents showed that the government was involved in drug trafficking and laundering drug profits. Harland Braun, Garner's defence attorney, doubted that the copies would have the impact his client hope for, but it could prove at useful bargaining chip. It was not Braun's opening, but close to. While cross examining one of the FBI agents who had participated in the Big Spender operation, Braun asked the agent if he knew anything about seized drug money being laundered by the federal government and then diverted to the Contras by CIA. After the day in court, Braun held his usual post trial spin session, where he was asked about his strange question to the FBI agent about the Contras and CIA. Braun explained that he was laying the groundwork for his defence: outrageous government conduct. Garner was a court certified expert, Braun pointed out and said, that Garner would explain in court how some of the cash he had been accused of stealing had been laundered by CIA and then used to buy arms for the. It got me again tonight. It had been a while and took me by surprise, but it was bad. Grief. Agonizing, overwhelming grief. A pain so enormous it took my breath away, making it impossible to cry. Would I never get over it? Wasn't 25 years long enough to pray I could have my baby back? I don't even know when I got pregnant. I don't remember the discussions that must have taken place between my mother and me. What I do remember is being taken to the finest hospital, rolled into the most sophisticated operating room, having my baby killed by one of the top doctors in the city. I also remember waking up and hearing women crying and screaming, including myself. I remember indescribable pain, blood--more blood than I had ever seen. Several days later, I remember being rushed in the middle of the night to an emergency room. I was hemorrhaging and fading in and out of consciousness from a raging fever. My medical records say that I was in the hospital for 6 days, underwent 2 D&C's, and was rolled back into the O.R. a final time for a complete hysterectomy. I don't know what stopped the surgeon, but he saved my life and my ability to have children. I had been saved from a septic therapeutic abortion. I was 15 years old. Since those horrible days in 1973, this has never once been spoken of. I grew up to become a professional with a loving husband and seven beautiful, healthy children. A miracle indeed considering those are not the odds for someone like me. I also know that keeping my shame and guilt silent is killing my baby over and over again. Yes, it was a baby, not a tissue, a mass, a "condition" that needed correcting. She was alive and real and would be 25 years old if I had given her the opportunity to live. My ignorance, fear, and youth were used against us. If anyone had told me of the secret shame, fear, pain, and lifelong regret, my baby would be alive today. If anyone had told me about the potential life-threatening or fatal medical complications, my baby would be alive today. If anyone had told me the truth, my baby would be alive today.

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Was large enough to be gripped comfortably; had knurled edges to improve grip; required only a quarter turn to open and re-secure; and was not child-resistant, but was coloured bright red. For consumers with arthritic hands, who are typical users of this product, the new design was a success. However, the new package was not child-resistant; some users had difficulty removing the tamper-evident plastic; and the product was more expensive in this form of packaging. Nevertheless, the example shows how package design can be sensitive to the needs of consumers. Packaging can also enhance compliance, reduce errors, and improve the quality of life and health for consumers. Of course, there are trade-offs in terms of the cost to produce such packaging as well as the effect on the environment. Other sections of this document provide detail on issues such as layout, design and compliance. Prescription medications are typically dispensed in one of two ways: in the original package provided by the manufacturer; or in a package provided by the pharmacist, such as pill vials or bottles for liquids. The following result can now be established. Lemma 5. If hospitals compete in quality, and face a centralised monopoly union, the pre-merger wage is always lower than the post-merger wage. Ldquo; the surgical experience so far from this trial suggests an acceptable drug-related toxicity and no signs that the drug is adversely affecting bleeding during surgery or wound healing, ” said dr.
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References 1 ; NABP. "Mississippi makes pharmacy history, " National Association of Boards of Pharmacy Newsletter, 27 6 ; , 86 1998 ; . 2 ; NABP. "NABP answers questions on DSM exams credentialing, " National Association of Boards of Pharmacy Newsletter, 27 6 ; , 126, 137 1998 ; . 3 ; Isreal, S.F., "Three new pharmacy laws you need to know about: Pharmacy practice act revisions, " Arkansas Pharmacists Association Legislative News 1999 ; . 4 ; Ferrell, B.G., "Clinical performance assessment using standardized patients: A primer, " Fam. Med., 27, 14-19 1995 ; . 5 ; Wallace P., "Following the threads of an innovation: The history of standardized patients in medical education, " Caduceus, 13 2 ; , 5-28 1997 ; . 6 ; Heard, J.K., Allen, R., Tank, P.W., Cason, G. J., Cantrell, M. and Wheeler, R. P., "Assessing clinical skills of medical students, " J. AR Med. Soc., 93 4 ; , 175-179 1996 ; . 7 ; Monaghan, M. S., Vanderbush, R. E., Gardner, S. F., Grady, A. R. and McKay, A.B., "Standardized patients: An ability-based assessment for the evaluation of clinical skills in traditional and nontraditional education, " Am. J. Pharm. Educ., 61, 337-344 1997 ; . 8 ; Colliver, J.A., Swartz, M.H. and Robbs, R.S., "The effect of using multiple standardized patients on the inter-case reliability of a large-scale standardized patient examination administered over an extended testing period, " Acad. Med., 73 10 ; , S81-S83 1998 ; . 9 ; Fielding, D.W., Page, G. G., Schulzer, M., Moody, K., Dyer, S., O'Byrne, C. and Rogers, T., "Developing an objective structured clinical examination for performance evaluation in pharmacy, " Am. J. Pharm. Educ., 57 suppl ; , 101S-102S 1993 ; . 10 ; Niehaus, A. H., DaRosa, D.A., Markwell, S.J. and Folse, R., "Is test security a concern when OSCE stations are repeated across clerkship rotations?" Acad. Med., 71 3 ; , 287-289 1996 ; . 11 ; Morrison, H., McNally, H., Wylie, C, McFaul, P. and Thompson, W. "The passing score in the objective structured clinical examination, " Med. Educ., 30, 345-348 1996, for instance, drugs. 1. 2. Hospital Medicine 1999; 60 10 ; : 705-709 The Practitioner 2001; 245: 830-837. The large horizontal exposure of over 2000 sq.meters at the Pottery Neolithic village of Sha'ar Hagolan revealed a well-planned village. Three massive courtyard buildings were excavated, each occupying a few hundred square meters. The appearance of massive architecture in the Pottery Neolithic period is unique, as hardly any architectural remains have been discovered from this period at this region in previous excavations. Formalized passageways, a wide street and a narrow alley separate the structures. Unlike the houses, which were built and repaired by the individual families, the resurfacing of the street shows maintenance effort made on the community level. This indicates sophisticated village planning and social organization. Building II, not yet completely uncovered, is at least 40 by 20 rich assemblage of anthropomorphic figurines were found, including 42 seated cowry figures, 4 pillar figurines, 2 limestone pebble figurines and one bent figurine. No other building in the Neolithic Near East produced so many art objects. A selection of these is on exhibit for five years in the Metropolitan Museum of Art in New York City. Guidance attached to clinical sections is at the end of each chapter. If guidance appears to be past its review date in the paper copy of the HJF, check the website for the most up to date version. Alternatively a copy can be obtained from the Formulary Pharmacist. 1976; 8-30 recommendations for the safe handling of parenteral antineoplastic drugs. AVENTIS PHARMACEUTICALS, INC., Plaintiff Counterclaim Defendant-Appellant, and MERRELL PHARMACEUTICALS, INC., AND CARDERM CAPITAL L.P., Plaintiffs-Appellants, v. BARR LABORATORIES, INC., Defendant Counterclaimant-Appellee, and TEVA PHARMACEUTICALS USA, INC., Defendant Appellee.
Even if JC were to survive, the IVH "could portend severe neurologic complications, including mental retardation and cerebal palsy." 55. Later, after absorbing the initial news about their son, Cmdr. and Mrs. Cibula asked Dr. McCaffrey whether anything that Mrs. Cibula had done during the pregnancy, such as her medications, may have caused JC's brain to bleed. said no. Dr. McCaffrey. Reaction with tubal Wheatcroft et al., 1994 ; or even muscular antigens Wheatcroft et al., 1997a ; . Moreover, their clinical signicance is not always obvious, as they can be detected in patients with iatrogenic POF or Turner syndrome Wheatcroft et al., 1994 ; . Cellular immunity. Abnormalities of the cellular immunity, i.e. T lymphocytes, macrophages and dendritic cells, also play an important role in autoimmune reactions, particularly in the development of autoimmune lesions. Some of these abnormalities have been recently described in POF and thus support the autoimmune mechanisms of this disease. As in other autoimmune diseases, the absolute count and percentage of peripheral blood T-lymphocytes, especially CD4 + T cells, has been found to be increased in patients with POF Mignot et al., 1989b ; . Flow cytometry has been used by several authors for further immunophenotyping peripheral lymphocyte subsets in POF patients, but some conicting results have been obtained. Thus it has been shown that POF patients had low levels of CD8 + CD57 + T cells cytotoxic T lymphocytes ; and an overall increase of the CD4 + CD8 + ratio Miyake et al., 1987; Chernyshov et al., 2001 ; , which is consistent with the abovementioned increase of the CD4 + count. However, no difference in the CD4 + CD8 + ratio was reported in another study Rabinowe et al., 1989 ; . A third group also described a decrease of this ratio in POF patients, yet suggested that this feature could also be caused by chronic hypoestrogenism Ho et al., 1993 ; . Increased circulating B-cells in POF patients have been reported to be independent of serum estrogen levels Hoek et al., 1995 ; and immunophenotyping demonstrated a high percentage of CD19 + CD5 + cells B2 cells involved in autoimmunity ; in POF patients Chernyshov et al., 2001 ; . Activated T cells also seem to be increased in POF as it has been shown that 3550% of these patients present a higher expression of the MHC class II molecules, especially HLA-DR, on their T lymphocytes than healthy control subjects Rabinowe et al., 1989; Nelson et al., 1991 ; . The alteration of cellular immunity has also been illustrated by a cutaneous candidine derived from Candida albicans ; delayed hypersensitivity test being negative in 50% of POF patients Hoek et al., 1995 ; . Finally, in vitro tests showed that blood monocytes from 20 to 46% of POF patients had an abnormal response to chemotactic agents Pekonen et al., 1986; Hoek et al., 1993 ; , whereas dendritic cells from 36% of the same patients presented a reduced capacity to aggregate with T-lymphocytes. Similar ndings have been reported in other autoimmune diseases, such as type I diabetes or Graves' disease Hoek et al., 1993 ; . Finally, the number as well as the activity of natural killer NK ; cells seemed to be reduced in POF patients Pekonen et al., 1986; Hoek et al., 1995 ; . The coexistence of an autoimmune ovarian inammation and an impaired cellular immune response further illustrates the complex defects of immune regulation in autoimmune ovarian disease. The involvement of cellular immunity in the pathogenesis of autoimmune ovarian disease has also been investigated in animal models, such as murine post-thymectomy oophoritis and active immunization with ovarian extracts. These experimental diseases cannot be described in detail here, but it should be mentioned that the autoimmune oophoritis which develops in these models can be transferred in some cases to healthy recipients by peripheral, lymph node, or splenic T-lymphocytes Damjanovic, 1991; Tung et al., 2001.

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Demographic data for the 12 patients whose biopsies were examined in this study are shown in Table 1. Although no CTGF protein expression was detected in the kidneys from the six untreated minimal change nephrotic syndrome patients Figure 1A ; , CTGF protein localized in the tubular epithelial cells in four of the six kidney tissues from minimal change nephrotic syndrome patients who had been treated or who had just finished their treatment with steroid pulse therapy Figure 1B ; . There were no differences in the demographic data between the CTGFpositive and -negative minimal change nephrotic syndrome patients data not shown ; . In light of these findings, we next examined the effects of DEX on the expression of CTGF mRNA in the kidneys of different mouse strains. DEX treatment significantly increased CTGF mRNA levels in the kidneys of C57B6 mice Figure 2A ; , had no effect in the kidneys of SJL mice Figure 2B ; , and slightly increased CTGF mRNA levels in the kidneys of Balb C and 129 mice data not shown ; . Interestingly, DEX significantly increased CTGF mRNA levels in the lungs of C57B6 4.3 0.5-fold, P 0.05 ; but not SJL mice after 3 hours. Regardless of DEX treatment, however, CTGF mRNA levels in the liver were significantly lower than those in the kidneys and lungs in both strains of mice. DEX slightly, but not significantly, increased CTGF mRNA levels in the kidneys of F1 C57B6 SJL ; mice to levels that were approximately midway between the levels found in C57B6 and SJL mice Figure 2C ; . Immunohistochemistry using an anti-CTGF antibody lo.
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